Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Mycobacterium mucogenicum
Introduction
Overview
Overview
Mycobacterium mucogenicum Etymology: mucogenicum, from the organism’s highly mucoid appearance.
Description
Description
Gram-positive, nonmotile, curved and acid-fast rods.
Colony characteristics
- Highly mucoid behavior of most strains on solid agar. Smooth and off-white on Middlebrook 7H10 agar
Physiology
- Rapid growth on Middlebrook 7H10 at 28°C to 37°C, but not at 42°C, within 2 – 4 days.
- Susceptible to amikacin, imipenem, cefoxitin, clarithromycin and ciprofloxacin.
- Resistant to isoniazid and rifampin.
Pathogenesis
Pathogenesis
- Posttraumatic skin infections,
- catheter sepsis and respiratory isolates without clinical significance except in immunocompromised hosts.
- Biosafety level 2
Type Strain
Type Strain
- First isolated in 1976 during an outbreak of peritonitis associated with automated peritoneal dialysis machines in the north-western United States.
- Strain ATCC 49650 = CCUG 47451 = CIP 105223 = DSM 44625 = JCM 13575.
Treatment
Treatment
Antimicrobial regimen
- In vitro susceptible agents: Aminoglycosides, Cefoxitin, Clarithromycin, Minocycline, Doxycycline, Quinolones, Trimethoprim/sulfamethoxazole, and Imipenem
References
References
- ↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). “An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases”. American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.
- Springer et al. 1995. Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int. J. Syst. Bacteriol., 45, 262-267.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]