Mycobacterium mucogenicum

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mycobacterium mucogenicum Etymology: mucogenicum, from the organism’s highly mucoid appearance.

Description

Gram-positive, nonmotile, curved and acid-fast rods.

Colony characteristics

Highly mucoid behavior of most strains on solid agar. Smooth and off-white on Middlebrook 7H10 agar

Physiology

Rapid growth on Middlebrook 7H10 at 28°C to 37°C, but not at 42°C, within 2 – 4 days.
Susceptible to amikacin, imipenem, cefoxitin, clarithromycin and ciprofloxacin.
Resistant to isoniazid and rifampin.

Pathogenesis

Posttraumatic skin infections,
catheter sepsis and respiratory isolates without clinical significance except in immunocompromised hosts.
Biosafety level 2

Type Strain

First isolated in 1976 during an outbreak of peritonitis associated with automated peritoneal dialysis machines in the north-western United States.
Strain ATCC 49650 = CCUG 47451 = CIP 105223 = DSM 44625 = JCM 13575.

Treatment

References

↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). “An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases”. American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.

Springer et al. 1995. Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int. J. Syst. Bacteriol., 45, 262-267.

Overview