
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Myelofibrosis MRI
Introduction
Overview
Overview
MRI may be helpful in the diagnosis of myelofibrosis. Findings on MRI suggestive of myelofibrosis include diffuse decrease in bone marrow signal intensity.
MRI
MRI
- MRI may be helpful in the diagnosis of myelofibrosis and can be useful in evaluating the stage and the progression of disease.
- Findings on MRI suggestive of myelofibrosis include:
- Diffuse decrease in bone marrow signal intensity[1][2][3]
- Very low, mainly homogeneous signal on both T1- and T2-weighted images[4]
- Foci of extramedullary hematopoiesis (EMH) involving the spine manifest as heterogeneous and predominantly hyperintense masses
- Foci of intracranial extramedullary hematopoiesis (EMH) manifest as masses of variable signal intensity[5]
Images
Images


References
References
- ↑ Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016
- ↑ Ueda F, Takashima T, Suzuki M, Kadoya M (1994). “MR diagnosis of myelofibrosis”. Radiat Med. 12 (3): 135–7. PMID 7972898.
- ↑ Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME (1986). “MR imaging in myelofibrosis”. J Comput Assist Tomogr. 10 (4): 634–6. PMID 3734203.
- ↑ Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J (1999). “Imaging findings in patients with myelofibrosis”. Eur Radiol. 9 (7): 1366–75. doi:10.1007/s003300050850. PMID 10460376.
- ↑ Koch BL, Bisset GS, Bisset RR, Zimmer MB (June 1994). “Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation”. AJR Am J Roentgenol. 162 (6): 1419–20. doi:10.2214/ajr.162.6.8192010. PMID 8192010.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
