Natural History Myoglobinuria does not lead to death, unless it is associated with the secondary complications of rhabdomyolysis, including hyperkalemia, hypocalcemia, and acute kidney injury.^[1] However, when it is associated with severe rhabdomyolysis, myoglobinuria-induced acute renal failure is a potentially lethal complication.

Complications’ and Prognosis In adults, myoglobinuria, due to rhabdomyolysis can be complicated by acute kidney injury, that requires hemodyalisis. In children, renal failure and acute kidney injury are also the most common complications.