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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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N-arachidonoyl-dopamine

Introduction

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N-arachidonoyl-dopamine, or NADA is a ligand (or chemical ‘key’) agonist (activator) to CB1 receptors which is an activation site for endocannabinoid and endovanilloid (aka vanilloid) ligands[1]. Specifically, NADA binds to both TRPV1 (a TRP-vanilloid cation channel receptor) and CB1 (an endocannabinoid receptor), a peculiarity among neurochemicals which normally bind to only one type of receptor.

References

References

  1. ↑ Ralevic V. (2003). “Cannabinoid modulation of peripheral autonomic and sensory neurotransmission”. European journal of pharmacology. 472 (1–2): 1–21. PMID 12860468. Unknown parameter |month= ignored (help)
External links

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