Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
NISCH syndrome
Introduction
Neonatal ichthyosis–sclerosing cholangitis syndrome (also known as “NISCH syndrome” and “Ichthyosis–sclerosing cholangitis syndrome”) is a cutaneous condition caused by mutations in the Claudin 1 gene.