N-Acetylglutamic acid

N-Acetylglutamic acid (abbreviated NAcGlu) is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetylglutamate synthase. Arginine is the activator for this reaction.

The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase.

NAcGlu activates carbamoyl phosphate synthase in the urea cycle.

• Glutamate
• Glutamic acid

• Diagram at biochemj.org

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