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Naratriptan description
Introduction
Description
Description
Naratriptan tablets, USP contain naratriptan as the hydrochloride, which is a selective 5-hydroxytryptamine1 receptor subtype agonist. Naratriptan hydrochloride is chemically designated as N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide monohydrochloride, and it has the following structure:
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The molecular formula is C17H25N3O2S•HCl, representing a molecular weight of 371.93. Naratriptan hydrochloride is an off-white to pale yellow crystalline powder that is sparingly soluble in water.
Each naratriptan tablet for oral administration contains naratriptan hydrochloride equivalent to 1 mg or 2.5 mg of naratriptan, respectively. Each tablet also contains the following inactive ingredients: anhydrous lactose, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, lactose monohydrate, hypromellose, titanium dioxide and triacetin. In addition the 2.5 mg tablet also contains iron oxide yellow and FD&C blue No.2 aluminum lake.[1]
References
References
Adapted from the FDA Package Insert.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]