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Nephrotic syndrome historical perspective

Introduction

Overview

Overview

In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy. In 1905, Müller described the term of “nephrosis” for non-inflammatory kidney diseases.

Historical Perspective

Historical Perspective

  • In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy.
  • In 1722, Theodore Zwinger of Basel described nephrotic syndrome in children, with decreased urine output due to “obstruction and compression of the tubules of the kidney.”
  • In 1827, Richard Bright described the triad of generalized edema, proteinuria, and kidney disease, as features of nephrotic syndrome.
  • In 1905, Müller described the term of “nephrosis” for non-inflammatory kidney diseases.[1]
References

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [3]