Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Neuroblastoma historical perspective
Introduction
Overview
Overview
Neuroblastoma was first described by Rudolf Virchow in 1864 as an abdominal tumor in a child as “glioma“. Felix Marchand described characteristics of tumors from adrenal medulla and sympathetic nervous system in 1891. James Homer wright in 1910, described circular clumps of bone marrow ( now named “Homer-Wright pseudorosettes) and advanced the understanding that tumor originated from primitive neural cells and could metastasize to bone.
Historical Perspective
Historical Perspective
- In 1864, Rudolf Virchow (german physician) first described an abdominal tumor in a child as “glioma“.[1]
- In 1891, Felix Marchand (german pathologist) described the characteristics of tumors from adrenal medulla and sympathetic nervous system.[2]
- In 1901, William Pepper described a neuroblastoma stage 4S presentation in infants that was metastatic to liver.
- In 1910, James Homer Wright described circular clumps of cells in bone marrow ( now named “Homer-Wright pseudorosettes) and advanced the understanding that tumor originated from primitive neural cells and could metastasize to bone.[3]
References
References
- ↑ . doi:10.5281/zenodo.1437314. Missing or empty
|title=(help) - ↑ Ritesh R. Kalaskar & Ashita R. Kalaskar (2016). “Neuroblastoma in early childhood: A rare case report and review of literature”. Contemporary clinical dentistry. 7 (3): 401–404. doi:10.4103/0976-237X.188579. PMID 27630510. Unknown parameter
|month=ignored (help) - ↑ Alexis B. Rothenberg, Walter E. Berdon, Giulio J. D’Angio, Darrell J. Yamashiro & Robert A. Cowles (2009). “Neuroblastoma-remembering the three physicians who described it a century ago: James Homer Wright, William Pepper, and Robert Hutchison”. Pediatric radiology. 39 (2): 155–160. doi:10.1007/s00247-008-1062-z. PMID 19034443. Unknown parameter
|month=ignored (help)
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]