Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Niclosamide
Introduction
| Niclosamide |
|---|
| YOMESAN® Package Insert |
| Clinical Pharmacology |
| Indications |
| Contraindications |
| Side Effects |
| Overdosage |
| Dosage |
Overview
Overview
Niclosamide is a teniacide (“tenia-” referring to tapeworm) in the anthelmintic family especially effective against cestodes that infect humans.
It is stressed that while anthelmintics are a drug familiy used to treat worm infections, Niclosamide is used specifically to treat tapeworms and is not effective against worms such as pinworms or roundworms.
It is a chewable tablet taken orally, dosage depending on type of worm and patient’s age and/or weight.
Niclosamide molecules are lethal to tapeworms upon contact.
Category
Category
Anthelmintic
US Brand Names
US Brand Names
NICLOCIDE®, YOMESAN® (DISCONTINUED)
FDA Package Insert
FDA Package Insert
Clinical Pharmacology | Indications | Contraindications | Side Effects | Overdosage | Dosage
Mechanism of Action
Mechanism of Action
Niclosamide uncouples oxidative phosphorylation in the tapeworm.[1]
References
References
- ↑ Weinbach EC, Garbus J (1969). “Mechanism of action of reagents that uncouple oxidative phosphorylation”. Nature. 221 (5185): 1016–8.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]