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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Nisoxetine

Introduction

Nisoxetine (LY-94939) is a drug which inhibits the reuptake of norepinephrine (noradrenaline). It is a racemic compound with two isomers.

Uses

Uses

Nisoxetine is not currently used in humans,[1] but was originally researched as an antidepressant and is now widely used in scientific research as a standard selective noradrenaline reuptake inhibitor.[2]

References

References

  1. ↑ Kelwala S, Stanley M, Gershon S. History of antidepressants: successes and failures. Journal of Clinical Psychiatry. 1983 May;44(5 Pt 2):40-8.PMID 6222036
  2. ↑ Graham D, Langer SZ. Advances in sodium-ion coupled biogenic amine transporters. Life Sciences. 1992;51(9):631-45.PMID 1501510

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]