Health Dictionary
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Nitrosylation
Introduction
Nitrosylation is a protein modification, in which a nitrosyl group is post-translationally added to a protein.
There are a range of enzymes that produce nitric oxide, and the frequent consequence of this production is nitrosylation.
S-nitrosylation is a biologically important reaction of nitric oxide; it refers to the conversion of thiol groups, including cysteine residues in proteins, to form S-nitrosothiols (RSNOs). S-Nitrosylation is a mechanism for dynamic, post-translational regulation of most or all major classes of protein.