Nocardiosis natural history, complications and prognosis

Complications of nocardial infections vary depending on what parts of the body are involved. Certain lung infections may lead to scarring and chronic shortness of breath. Skin infections may lead to scarring or disfigurement. Brain abscesses may lead to loss of neurological function.

Approximately 10% of cases with uncomplicated pneumonia are fatal. The case-fatality rate increases with overwhelming infection, disseminated disease, or brain abscess. Surgical drainage may be indicated and may improve patient outcome.

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