Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Nodular fasciitis
Introduction
Synonyms and keywords: Nodular pseudosarcomatous fasciits; subcutaneous pseudosarcomatous fibromatosis
Overview
Overview
Nodular fasciitis, also known as Nodular pseudosarcomatous fasciits and Subcutaneous pseudosarcomatous fibromatosis[1]:992, is a benign[2] lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk. Commonly mistaken for a sarcoma.
Pathophysiology
Pathophysiology
Histology
- Histologically vast array of patterns.
- Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.
- Essentially spindle cell proliferation.
- Stroma is rich in collagen and/or myxoid ground substance.
Natural History and Prognosis
Natural History and Prognosis
Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered. It evolves rapidly, but is usually less than 3Â cm in diameter. There is an extremely low incidence of recurrence after resection.
References
References
- ↑ Freedberg, et al. (2003). Fitzpatrick’s Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
- ↑ Sailon AM, Cappuccino G, Hameed M, Fleegler EJ (2008). “Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report”. Eplasty. 8: e38. PMC 2491338. PMID 18725954.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]