Non-Hodgkin lymphoma physical examination

Common physical examination findings of non-Hodgkin lymphoma include fever, pruritus, petechiae, chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly, peripheral lymphadenopathy, seizures, and central lymphadenopathy.

Physical examination of patients with Non Hodgkin Lymphoma is usually remarkable for fever, pruritus, petechiae, chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly and peripheral lymphadenopathy.^[1][2][3]

• Patients with Non Hodgkin Lymphoma usually appear cachectic
• Pemberton’s sign: development of suffusion, plethora, or duskiness upon elevation of the arms above the head in patients with superior vena cava (SVC) syndrome.

• Low to high-grade fever
• Tachypnea
• Kussmal respirations may be present in advanced SVCS.
• Asymmetric pulse

• Skin examination of patients with Non Hodgkin Lymphoma include:
  • Pallor
  • Pruritus
  • Petechiae
  • Single or localized cluster of erythematous skin nodules
  • Superficial ulcers

• Abnormalities of the head/hair may include:
  • Icteric sclera
  • Nystagmus
• Patient with superior vena cava syndrome present with:
  • Facial tenderness
  • Swelling of the face
  • Facial flushing/redness face or cheeks
  • Drooping eyelid
  • Swelling around the eye
  • Swelling of the whites of the eyes

• Cervical lymphadenopathy may be present
• Jugular venous distension
• Hepatojugular reflux

• Thoracic masses suggestive of central lymphadenopathy
• Chest tenderness
• Pleural effusion may be present and manifestations may include:
  • Lungs are hyporesonant
  • Decreased breath sounds
  • Asymmetric chest expansion
  • Wheezing

• Cardiovascular examination of patients with Non Hodgkin Lymphoma is usually normal.

• Abdominal examination of patients with Non Hodgkin Lymphoma include:
  • Abdominal distension
  • Abdominal tenderness
  • Abdominal mass
• Hepatomegaly
  • splenomegaly

• Back examination of patients with Non Hodgkin Lymphoma is usually normal.

• Genitourinary examination of patients with Non Hodgkin Lymphoma is usually normal.

• Neuromuscular examination of patients with Non Hodgkin Lymphoma is usually normal.

• Extremities examination of patients with Non Hodgkin Lymphoma include:
  • Peripheral lymphadenopathy
  • Joint pain

• Seizures

• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]

• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]
• 
  :Non hodgkin’s lymphoma. Adapted from Dermatology Atlas.^[4]