
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Nonreciprocal translocation
Introduction
In genetics, a nonreciprocal translocation is a chromosome abnormality referring to the one-way transfer of a chromosomal segment from one non-homologous chromosome to another. It is a type of chromosomal translocation, along with reciprocal (non-Robertsonian) translocation. Unlike reciprocal translocation however, nonreciprocal translocation does not involve the exchange of chromosomal segments between two chromosomes. Nonreciprocal translocation is a one-way transfer, rather than two-way exchange, of one chromosomal segment from its original locus to a locus on a non-homologous chromosome.
