Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
OTUD1
Introduction
OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. [1]
Function
Function
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
Further reading
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.