
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Odynophagia differential diagnosis
Introduction

Overview
Overview
Odynophagia should be differentiated from dysphagia (difficulty in swallowing). There are many causes of odynophagia. They can also be differentiated with help of appropriate H & E and diagnostic procedures.[1][2][3][4][5]
Differentiating odynopaghia from dysphagia:
Differentiating odynopaghia from dysphagia:
| Factor | Odynopagia | Dysphagia |
|---|---|---|
| Defination | Pain in swallowing | Inability to start or continue to swallow |
| Pathophysiology | Irritation of sensory nerves | Motor nerves paralysis or mechanical obstruction |
| Involved areas | Pharynx and esophagus | Motor nerves or esophagus |
Odynophagia differentials:
Odynophagia differentials:
| Causes | Pain | History finding | Examination finding | Diagnostic test |
|---|---|---|---|---|
| URTI | Acute pain | Change in voice, fever, runny nose | inflamed oral mucosa, enlarged lymph nodes or tonsils | Oral swab culture |
| Tumors | Dull Pain | Loss of weight and appetite, risk factors, may have dysphagia | swelling may be seen, tumor may spread to lymph nodes | Endoscopy |
| Foreign body | Acute pain | History of foreign body intake | Foreign body may be seen, surrounding area may be inflamed | Laryngoscopy |
| GERD | Burning pain | Pain worse at night, decrease food intake but normal appetite | Oral mucosa normal, mild tender epigastrium | Manomatary |
| Esophagitis | Burning pain | Retrosternal pain on swallowing, food aversion | Oral mucosa normal | Endoscopy |
References
References
- β SopeΓ±a B, Limeres J, GarcΓa-Caballero L, Diniz-Freitas M, Seoane J, Diz P (2018). “A Dramatic Case of Odynophagia”. Dysphagia. 33 (1): 133β135. doi:10.1007/s00455-017-9861-8. PMIDΒ 29128948.
- β Fukuda S, Watanabe N, Domen T, Ishioka M, Sawaguchi M, Ohba R; et al. (2018). “A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer”. Clin J Gastroenterol. 11 (1): 38β41. doi:10.1007/s12328-017-0797-1. PMIDΒ 29124648.
- β Chi TH, Hung CC, Chen RF, Yuan CH, Chen JC (2017). “Spontaneous retropharyngeal emphysema: A case report”. Niger J Clin Pract. 20 (9): 1213β1215. doi:10.4103/njcp.njcp_3_16. PMIDΒ 29072250.
- β Jovov B, Reed CC, Shaheen NJ, Pruitt A, Ferrell K, Orlando GS; et al. (2017). “Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease”. Dig Dis Sci. doi:10.1007/s10620-017-4815-4. PMIDΒ 29071486.
- β Althuwaini S, Bamehriz F, Aldohayan A, Alshammari W, Alhaidar S, Alotaibi M; et al. (2017). “Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy”. Obes Surg. doi:10.1007/s11695-017-2971-4. PMIDΒ 29043549.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sunny Kumar MD [2]
