Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Oligomycin
Introduction
Oligomycins are macrolides created by Streptomyces that can be poisonous to other organisms.
Function
They have use as antibiotics.
In addition, oligimycin inhibits ATP synthase by blocking its proton channel, which is necessary for oxidative phosphorylation of ADP to ATP (energy production).
Administering oligomycin to an individual can result in very high levels of lactate accumulating in the blood and urine.