
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Oliguria with fatigue, somatic pain, vomiting, diarrhea, and edema
Introduction
Abbreviations: ABG = Arterial blood gases, BUN = Blood urea nitrogen, CBC = Complete blood count, CT = Computed tomography, CRP = C – reactive protein, ECG = Electrocardiogram, ESR = Erythrocyte sedimentation rate, IVP = Intravenous pyelography, KFT = Kidney function test, GI = Gastrointestinal, GFR = Glomerular filtration rate, MRI = Magnetic resonance imaging, PT = Prothrombin time
| Etiology | Clinical manifestations | Paraclinical findings | Comments | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms and signs | Lab findings | Imaging | ||||||||||||||||||||
| Fatigue/
Lethargy |
Thirst | Dizziness/
Confusion |
Muscle weakness/
cramp |
Somatic/
visceral pain |
Vomiting | Diarrhea | Tachypnea | Edema | Blood indices | Renal Funtion test | Electrolytes | Urine analysis | ABG | Other | Ultrasound | X-ray | CT | MRI | Other | |||
| Prerenal causes | Drugs/toxins[1][2] | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | Not applicable | βBUN, βCr, βCK | βK, βMg, βCa, βP | Ingested drug, Glucose, Aminoacid, Phosphate, Ketone, Hyaline cast, RBC | βLactate, Metabolic acidosis | Toxicology, Rapid immunoassay | Nephropathy | Radioopaque substances, Ingested drug packets | Not applicable | Not applicable | – | – |
| Renal causes | Acute interstitial nephritis[3][4] | +/- | – | +/- | – | +/- | +/- | +/- | +/- | +/- | Eosinophilia | βBUN, βCr, βFENa | Not applicable | Eosinophiluria, Sterile pyuria, Microscopic hematuria, Proteinuria | Not applicable | βTotal IgG, βIgG4 | Normal-sized kidneys | Not applicable | Not applicable | Not applicable | – | History of long term analgesic use |
| Cancer[5][6] | + | – | – | – | +/- | +/- | +/- | – | +/- | Normocytic or microcytic anemia, Leukocytosis or lymphocytosis, βReticulocytes, Thrombocytopenia | βGFR, βBUN, βCr, βErythropoietin | βNa, βK, βMg, βP, βCa | Gross hematuria | Not applicable | LFT | Fluid collection and morphological change, Flank mass | Calcification and widened mediastinum, Filling defects in barium contrast | Metastasis and staging, Cystic and solid masses, Lymph node, renal vein, and inferior vena cava involvement | Soft tissue invasion and staging | Malignant cystic lesions percutaneous cyst puncture | Renal cell carcinoma types: Clear cell (75%), Chromophilic (15%), Chromophobic (5%), Oncocytoma (3%), Collecting duct (2%) | |
| Hemolytic uremic syndrome[7][8][9] | +/- | – | +/- | +/- | +/- | + | + | – | +/- | Severe anemia, Thrombocytopenia, β aPTT | βBUN, βCr | Not applicable | Mild proteinuria, Red blood cells, Red blood cell casts | Not applicable | Schistocytes, βFDP and D-dimer, β Bilirubin, βLDH, βHaptoglobin, Stool culture (for E coli 0157:H7 or shigella), βADAMTS-13 activity | Ruling out obstruction | Not applicable | Not applicable | Not applicable | Diffuse thickening of the glomerular capillary wall, Swelling of endothelial cells, Fibrin thrombi in renal biopsy | – | |
References
- β Toto RD, Mitchell HC, Lee HC, Milam C, Pettinger WA (October 1991). “Reversible renal insufficiency due to angiotensin converting enzyme inhibitors in hypertensive nephrosclerosis”. Ann. Intern. Med. 115 (7): 513β9. PMIDΒ 1883120.
- β Bismuth C, Gaultier M, Conso F, Efthymiou ML (1973). “Hyperkalemia in acute digitalis poisoning: prognostic significance and therapeutic implications”. Clin. Toxicol. 6 (2): 153β62. doi:10.3109/15563657308990513. PMIDΒ 4715199.
- β Schwarz A, Krause PH, Kunzendorf U, Keller F, Distler A (September 2000). “The outcome of acute interstitial nephritis: risk factors for the transition from acute to chronic interstitial nephritis”. Clin. Nephrol. 54 (3): 179β90. PMIDΒ 11020015.
- β Praga M, GonzΓ‘lez E (June 2010). “Acute interstitial nephritis”. Kidney Int. 77 (11): 956β61. doi:10.1038/ki.2010.89. PMIDΒ 20336051.
- β Gudbjartsson T, Thoroddsen A, Petursdottir V, Hardarson S, Magnusson J, Einarsson GV (December 2005). “Effect of incidental detection for survival of patients with renal cell carcinoma: results of population-based study of 701 patients”. Urology. 66 (6): 1186β91. doi:10.1016/j.urology.2005.07.009. PMIDΒ 16360438.
- β Skinner DG, Colvin RB, Vermillion CD, Pfister RC, Leadbetter WF (November 1971). “Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases”. Cancer. 28 (5): 1165β77. PMIDΒ 5125665.
- β Noris M, Remuzzi G (April 2005). “Hemolytic uremic syndrome”. J. Am. Soc. Nephrol. 16 (4): 1035β50. doi:10.1681/ASN.2004100861. PMIDΒ 15728781.
- β Goodship TH, Cook HT, Fakhouri F, Fervenza FC, FrΓ©meaux-Bacchi V, Kavanagh D, Nester CM, Noris M, Pickering MC, RodrΓguez de CΓ³rdoba S, Roumenina LT, Sethi S, Smith RJ (March 2017). “Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference”. Kidney Int. 91 (3): 539β551. doi:10.1016/j.kint.2016.10.005. PMIDΒ 27989322.
- β Loirat C, Fakhouri F, Ariceta G, Besbas N, Bitzan M, Bjerre A, Coppo R, Emma F, Johnson S, Karpman D, Landau D, Langman CB, Lapeyraque AL, Licht C, Nester C, Pecoraro C, Riedl M, van de Kar NC, Van de Walle J, Vivarelli M, FrΓ©meaux-Bacchi V (January 2016). “An international consensus approach to the management of atypical hemolytic uremic syndrome in children”. Pediatr. Nephrol. 31 (1): 15β39. doi:10.1007/s00467-015-3076-8. PMIDΒ 25859752.
Editor-In-Chief:
C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
