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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Opiorphin

Introduction

Opiorphin is a chemical compound isolated from human saliva. Initial research with mice shows the compound has a painkilling effect of up to six times that of morphine. It works by stopping the normal breakdown of natural pain-killing opioids in the spine, called enkephalins. It is a relatively simple molecule that should be possible to replicate and synthesize in large quantities.[1][2][3][4]

References

  1. ↑ Wisner, Anne (November 13, 2006). “Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways”. Proceedings of the National Academy of Sciences. 103: 17979. doi:10.1073/pnas.0605865103. Unknown parameter |coauthors= ignored (help); Check date values in: |date= (help); |access-date= requires |url= (help)
  2. ↑ Andy Coghlan (November 13, 2006). “Natural-born painkiller found in human saliva”. New Scientist.
  3. ↑ “Natural chemical ‘beats morphine‘“. BBC News. November 14,2006. Check date values in: |date= (help)
  4. ↑ Mary Beckman (November 13, 2006). “Prolonging Painkillers”. ScienceNOW.

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