Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Orlistat overdose
Introduction
Overdosage topics
Overdose
Single doses of 800 mg XENICAL and multiple doses of up to 400 mg three times a day
for 15 days have been studied in normal weight and obese subjects without significant
adverse findings. Return to top
Treatment
Should a significant overdose of XENICAL occur, it is recommended that the patient be
observed for 24 hours. Based on human and animal studies, systemic effects attributable
to the lipase- inhibiting properties of orlistat should be rapidly reversible. Return to top
Adapted from the FDA Package Insert.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]