Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Orotic acid
Introduction
Orotic acid, also known as pyrimidinecarboxylic acid or vitamin B13. Historically it was believed to be a vitamin but this is now known not to be the case. It is manufactured in the body by intestinal flora. It is sometimes used as a mineral carrier in some dietary supplements (to increase their bioavailability), most commonly for lithium.
Pathology
Pathology
A buildup can lead to orotic aciduria.
In ornithine transcarbamoylase deficiency excess carbamoyl phospate is converted into orotic acid. Leading to typical finding of increased urine orotic acid excretion in this disorder of the urea cycle.
External links
External links
- Orotic+Acid at the US National Library of Medicine Medical Subject Headings (MeSH)
- Overview at ggc.org
- Overview at greatvistachemicals.com
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]