Developer site: The content shown here is test data.

MyEClinic
MyEClinic
Health Dictionary AI Health Chat Find an Online Doctor
A serene Zen garden with raked sand and smooth stones, symbolising clarity and calm

Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

Back to skin conditions

Osteochondroma classification

Introduction

Overview

Overview

Osteochondromas may be classified into 2 subtypes: solitary osteochondromas (non-hereditary) and multiple osteochondromas (hereditary).[1]

Classification

Classification

The table below differentiates between the 2 subtypes of osteochondromas:[1][2][3][4][5][6][7][8]

Type of Osteochondroma Features
Solitary osteochondroma
  • Non-hereditary
  • 85% of osteochondromas
  • No genetic mutations
  • Located in long bones
  • Onset is in early adolescence
Multiple osteochondromas
  • Hereditary
  • Approximately 20% of osteochondromas
  • Related genetic mutations EXT-1 and EXT-2
  • Early onset of disease (newborn or children)
References

References

  1. ↑ 1.0 1.1 Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M (2008). “Osteochondromas: review of the clinical, radiological and pathological features”. In Vivo (Athens, Greece). 22 (5): 633–46. PMID 18853760.
  2. ↑ Kushner BH, Roberts SS, Friedman DN, Kuk D, Ostrovnaya I, Modak S, Kramer K, Basu EM, Cheung NK (June 2015). “Osteochondroma in long-term survivors of high-risk neuroblastoma”. Cancer. 121 (12): 2090–6. doi:10.1002/cncr.29316. PMC 4970322. PMID 25728463.
  3. ↑ Marcovici PA, Berdon WE, Liebling MS (March 2007). “Osteochondromas and growth retardation secondary to externally or internally administered radiation in childhood”. Pediatr Radiol. 37 (3): 301–4. doi:10.1007/s00247-006-0382-0. PMID 17211603.
  4. ↑ Faraci M, Bagnasco F, Corti P, Messina C, Fagioli F, Podda M, Prete A, Caselli D, Lanino E, Dini G, Rondelli R, Haupt R (October 2009). “Osteochondroma after hematopoietic stem cell transplantation in childhood. An Italian study on behalf of the AIEOP-HSCT group”. Biol. Blood Marrow Transplant. 15 (10): 1271–6. doi:10.1016/j.bbmt.2009.06.003. PMID 19747635.
  5. ↑ Pannier S, Legeai-Mallet L (March 2008). “Hereditary multiple exostoses and enchondromatosis”. Best Pract Res Clin Rheumatol. 22 (1): 45–54. doi:10.1016/j.berh.2007.12.004. PMID 18328980.
  6. ↑ Bovée JV (February 2008). “Multiple osteochondromas”. Orphanet J Rare Dis. 3: 3. doi:10.1186/1750-1172-3-3. PMC 2276198. PMID 18271966.
  7. ↑ Schmale GA, Conrad EU, Raskind WH (July 1994). “The natural history of hereditary multiple exostoses”. J Bone Joint Surg Am. 76 (7): 986–92. doi:10.2106/00004623-199407000-00005. PMID 8027127.
  8. ↑ Wicklund CL, Pauli RM, Johnston D, Hecht JT (January 1995). “Natural history study of hereditary multiple exostoses”. Am. J. Med. Genet. 55 (1): 43–6. doi:10.1002/ajmg.1320550113. PMID 7702095.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]