Health Dictionary
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PGPEP1
Introduction
The PGPEP1 gene in humans encodes the enzyme Pyroglutamyl-peptidase I.[1]
Further reading
Further reading
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). “Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes”. Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Valdivia A, Irazusta J, Fernández D, et al. (2005). “Pyroglutamyl peptidase I and prolyl endopeptidase in human semen: increased activity in necrozoospermia”. Regul. Pept. 122 (2): 79–84. doi:10.1016/j.regpep.2004.05.005. PMID 15380924.
- Minderman H, O’Loughlin KL, Pendyala L, Baer MR (2004). “VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein”. Clin. Cancer Res. 10 (5): 1826–34. doi:10.1158/1078-0432.CCR-0914-3. PMID 15014037.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Dando PM, Fortunato M, Strand GB, et al. (2003). “Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme”. Protein Expr. Purif. 28 (1): 111–9. doi:10.1016/S1046-5928(02)00632-0. PMID 12651114.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gil J, Larrinaga G, Meana JJ, et al. (2002). “Regional and subcellular distribution of soluble aminopeptidase in the human and the rat brain: a comparative study”. Neuropeptides. 35 (5–6): 276–84. doi:10.1054/npep.2001.0870. PMID 12030812.
- Charli JL, Mendez M, Vargas MA, et al. (1990). “Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices”. Neuropeptides. 14 (3): 191–6. doi:10.1016/0143-4179(89)90044-9. PMID 2575716.