
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions โ written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
PIK3R5
Introduction
Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene.[1][2]
References
References
- โ 1.0 1.1 Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K, Schultz G, Nurnberg B (Jan 2003). “Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma”. J Cell Biol. 160 (1): 89โ99. doi:10.1083/jcb.200210115. PMCย 2172741. PMIDย 12507995.
- โ “Entrez Gene: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101”.
Further reading
Further reading
- Johnson C, Marriott SJ, Levy LS (2007). “Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival”. Oncogene. 26 (49): 7049โ57. doi:10.1038/sj.onc.1210504. PMIDย 17486067.
- Rual JF, Venkatesan K, Hao T, et al. (2005). “Towards a proteome-scale map of the human protein-protein interaction network”. Nature. 437 (7062): 1173โ8. doi:10.1038/nature04209. PMIDย 16189514.
- Suire S, Coadwell J, Ferguson GJ, et al. (2005). “p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma”. Curr. Biol. 15 (6): 566โ70. doi:10.1016/j.cub.2005.02.020. PMIDย 15797027.
- Voigt P, Brock C, Nรผrnberg B, Schaefer M (2005). “Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma”. J. Biol. Chem. 280 (6): 5121โ7. doi:10.1074/jbc.M413104200. PMIDย 15611065.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121โ7. doi:10.1101/gr.2596504. PMCย 528928. PMIDย 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899โ903. doi:10.1073/pnas.242603899. PMCย 139241. PMIDย 12477932.
- Metjian A, Roll RL, Ma AD, Abrams CS (1999). “Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus”. J. Biol. Chem. 274 (39): 27943โ7. doi:10.1074/jbc.274.39.27943. PMIDย 10488142.
- Krugmann S, Hawkins PT, Pryer N, Braselmann S (1999). “Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits”. J. Biol. Chem. 274 (24): 17152โ8. doi:10.1074/jbc.274.24.17152. PMIDย 10358071.
