
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
POLR1B
Introduction
DNA-directed RNA polymerase I subunit RPA2 is an enzyme that in humans is encoded by the POLR1B gene.[1]
Further reading
Further reading
- Seither P, Zatsepina O, Hoffmann M, Grummt I (1997). “Constitutive and strong association of PAF53 with RNA polymerase I.”. Chromosoma. 106 (4): 216–25. doi:10.1007/s004120050242. PMID 9254723.
- Miller G, Panov KI, Friedrich JK (2001). “hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters”. EMBO J. 20 (6): 1373–82. doi:10.1093/emboj/20.6.1373. PMC 145519. PMID 11250903.
- Seither P, Iben S, Thiry M, Grummt I (2002). “PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I”. Biol. Chem. 382 (8): 1163–70. doi:10.1515/BC.2001.146. PMID 11592397.
- Shiau AK, Barstad D, Radek JT (2002). “Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism”. Nat. Struct. Biol. 9 (5): 359–64. doi:10.1038/nsb787. PMID 11953755.
- Egea PF, Mitschler A, Moras D (2002). “Molecular recognition of agonist ligands by RXRs”. Mol. Endocrinol. 16 (5): 987–97. doi:10.1210/me.16.5.987. PMID 11981034.
- Strausberg RL, Feingold EA, Grouse LH (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Bouwmeester T, Bauch A, Ruffner H (2004). “A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway”. Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
- Yamamoto K, Yamamoto M, Hanada K (2004). “Multiple Protein-Protein Interactions by RNA Polymerase I-Associated Factor PAF49 and Role of PAF49 in rRNA Transcription”. Mol. Cell. Biol. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256. PMID 15226435.
- Philimonenko VV, Zhao J, Iben S (2005). “Nuclear actin and myosin I are required for RNA polymerase I transcription”. Nat. Cell Biol. 6 (12): 1165–72. doi:10.1038/ncb1190. PMID 15558034.
- Hillier LW, Graves TA, Fulton RS (2005). “Generation and annotation of the DNA sequences of human chromosomes 2 and 4”. Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
- Zhang C, Comai L, Johnson DL (2005). “PTEN Represses RNA Polymerase I Transcription by Disrupting the SL1 Complex”. Mol. Cell. Biol. 25 (16): 6899–911. doi:10.1128/MCB.25.16.6899-6911.2005. PMC 1190253. PMID 16055704.
- Percipalle P, Fomproix N, Cavellán E (2006). “The chromatin remodelling complex WSTF–SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription”. EMBO Rep. 7 (5): 525–30. doi:10.1038/sj.embor.7400657. PMC 1479564. PMID 16514417.
- Panova TB, Panov KI, Russell J, Zomerdijk JC (2006). “Casein Kinase 2 Associates with Initiation-Competent RNA Polymerase I and Has Multiple Roles in Ribosomal DNA Transcription”. Mol. Cell. Biol. 26 (16): 5957–68. doi:10.1128/MCB.00673-06. PMC 1592790. PMID 16880508.
- Johnson SS, Zhang C, Fromm J (2007). “Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases”. Mol. Cell. 26 (3): 367–79. doi:10.1016/j.molcel.2007.03.021. PMID 17499043.
