Health Dictionary
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PPP3CB
Introduction
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PP2BB) is an enzyme that in humans is encoded by the PPP3CB gene.[1][2][3][4]
References
References
- ↑ Universal protein resource accession number P16298 for “Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform” at UniProt.
- ↑ Giri PR, Higuchi S, Kincaid RL (Jan 1992). “Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit”. Biochem Biophys Res Commun. 181 (1): 252–8. doi:10.1016/S0006-291X(05)81410-X. PMID 1659808.
- ↑ Guerini D, Krinks MH, Sikela JM, Hahn WE, Klee CB (Mar 1990). “Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase”. DNA. 8 (9): 675–82. doi:10.1089/dna.1.1989.8.675. PMID 2558868.
- ↑ “Entrez Gene: PPP3CB protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform”.
Further reading
Further reading
- Chen MX, Chen YH, Cohen PT (1992). “Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases”. FEBS Lett. 306 (1): 54–8. doi:10.1016/0014-5793(92)80836-6. PMID 1321058.
- McPartlin AE, Barker HM, Cohen PT (1991). “Identification of a third alternatively spliced cDNA encoding the catalytic subunit of protein phosphatase 2B beta”. Biochim. Biophys. Acta. 1088 (2): 308–10. doi:10.1016/0167-4781(91)90069-x. PMID 1848109.
- Guerini D, Klee CB (1990). “Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain”. Proc. Natl. Acad. Sci. U.S.A. 86 (23): 9183–7. doi:10.1073/pnas.86.23.9183. PMC 298458. PMID 2556704.
- Shibasaki F, McKeon F (1995). “Calcineurin functions in Ca(2+)-activated cell death in mammalian cells”. J. Cell Biol. 131 (3): 735–43. doi:10.1083/jcb.131.3.735. PMC 2120616. PMID 7593193.
- Muramatsu T, Kincaid RL (1993). “Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha)”. Biochim. Biophys. Acta. 1178 (1): 117–20. doi:10.1016/0167-4889(93)90117-8. PMID 8392375.
- Kissinger CR, Parge HE, Knighton DR, et al. (1996). “Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex”. Nature. 378 (6557): 641–4. doi:10.1038/378641a0. PMID 8524402.
- Wang MG, Yi H, Guerini D, et al. (1997). “Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21→q22 and 2p16→p15 respectively”. Cytogenet. Cell Genet. 72 (2–3): 236–41. doi:10.1159/000134198. PMID 8978785.
- Sun L, Youn HD, Loh C, et al. (1998). “Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes”. Immunity. 8 (6): 703–11. doi:10.1016/S1074-7613(00)80575-0. PMID 9655484.
- Aramburu J, Garcia-Cózar F, Raghavan A, et al. (1998). “Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT”. Mol. Cell. 1 (5): 627–37. doi:10.1016/S1097-2765(00)80063-5. PMID 9660947.
- Okamura H, Aramburu J, GarcÃa-RodrÃguez C, et al. (2000). “Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity”. Mol. Cell. 6 (3): 539–50. doi:10.1016/S1097-2765(00)00053-8. PMID 11030334.
- Frey N, Richardson JA, Olson EN (2001). “Calsarcins, a novel family of sarcomeric calcineurin-binding proteins”. Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14632–7. doi:10.1073/pnas.260501097. PMC 18970. PMID 11114196.
- Esau C, Boes M, Youn HD, et al. (2001). “Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells”. J. Exp. Med. 194 (10): 1449–59. doi:10.1084/jem.194.10.1449. PMC 2193671. PMID 11714752.
- Frey N, Olson EN (2002). “Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins”. J. Biol. Chem. 277 (16): 13998–4004. doi:10.1074/jbc.M200712200. PMID 11842093.
- Banerjee A, Banks AS, Nawijn MC, et al. (2002). “Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp”. J. Immunol. 168 (9): 4277–81. doi:10.4049/jimmunol.168.9.4277. PMID 11970967.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). “Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha”. Virology. 303 (1): 174–80. doi:10.1006/viro.2002.1676. PMID 12482669.
- Genescà L, Aubareda A, Fuentes JJ, et al. (2003). “Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life”. Biochem. J. 374 (Pt 2): 567–75. doi:10.1042/BJ20030267. PMC 1223619. PMID 12809556.
- Bell O, Gaberman E, Kilav R, et al. (2005). “The protein phosphatase calcineurin determines basal parathyroid hormone gene expression”. Mol. Endocrinol. 19 (2): 516–26. doi:10.1210/me.2004-0108. PMID 15514034.