Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Papillary thyroid cancer biopsy
Introduction
Overview
Overview
On biopsy, papillary thyroid cancer is characterized by trabecular, solid, follicular tumor cells that invade tumor capsule or surrounding vascular structures.
Key Biopsy Findings in Follicular Thyroid Cancer
Key Biopsy Findings in Follicular Thyroid Cancer
- Characteristic Orphan Annie eye nuclear inclusions (nuclei with uniform staining, which appear empty)[1] and psammoma bodies on light microscopy. The former is useful in identifying the follicular variant of papillary thyroid carcinomas.[2]
- Histologically papillary carcinoma demonstrates ‘delicate stalks of epithelial cells’ which account for its name.
Reference
Reference
- ↑ “Papillary Carcinoma of Thyroid (Hi Pow)”. University of Connecticut Health Center. Retrieved 2008-09-14.
- ↑ Yang GC, Liebeskind D, Messina AV (2001). “Ultrasound-guided fine-needle aspiration of the thyroid assessed by Ultrafast Papanicolaou stain: data from 1135 biopsies with a two- to six-year follow-up”. Thyroid. 11 (6): 581–89. doi:10.1089/105072501750302895. PMID 11442006.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]