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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Papular purpuric gloves and socks syndrome

Introduction

Synonyms and keywords: PPGSS

Overview

Overview

Papular purpuric gloves and socks syndrome (PPGSS) is an uncommon cutaneous condition with a typical purpuric exanthem limited to hands and feet.

Causes

Causes

Epidemiology and Demographics

Epidemiology and Demographics

  • PPGSS occurs primarily in teenagers and young adults.
Natural History, Complications and Prognosis

Natural History, Complications and Prognosis

  • Rash and fever completely resolved in less than 3 days.
  • The disease has a short course and a benign prognosis.
Diagnosis

Diagnosis

Symptoms

PPGSS is characterized by

Physical Examination

Extremities

Laboratory Findings

  • All laboratory tests are normal.
  • Positive serology for Parvovirus B19. IgM is positive but not IgG.[3]
  • Viral DNA test to detect the virus.
References

References

  1. ↑ Fölster-Holst R, Kreth HW (2009). “Viral exanthems in childhood–infectious (direct) exanthems. Part 2: Other viral exanthems”. J Dtsch Dermatol Ges. 7 (5): 414–9. doi:[//doi.org/10.1111%2Fj.1610-%0A%0A0387.2008.06869.x 10.1111/j.1610- 0387.2008.06869.x] Check |doi= value (help). PMID 18808380. Unknown parameter |month= ignored (help); line feed character in |author= at position 15 (help); line feed character in |journal= at position 3 (help); line feed character in |doi= at position 16 (help)
  2. ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews’ Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. line feed character in |author= at position 43 (help)
  3. ↑ Parez N, Dehée A, Michel Y, Veinberg F, Garbarg-Chenon A (2009). “Papular-purpuric gloves and socks syndrome associated with B19V infection in a 6-year-old child”. J. Clin. Virol. 44 (2): 167–9. doi:10.1016/j.jcv.2008.11.013. PMID 19129008. Unknown parameter |month= ignored (help); line feed character in |title= at position 44 (help)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]