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Parathyroid adenoma epidemiology and demographics

Introduction

Overview

Overview

A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism[1]. A double adenomas the culprit in 4% to 5%, and parathyroid hyperplasia in 10% to 12%[2]. Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease. Adenomas are most common in patients 50 to 70 years old.They can occur at any age. Women are affected 3-times as often as men

Epidemiology and Demographics

Epidemiology and Demographics

Prevalence

  • A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism[3].
  • Approximately 100,000 Americans develop primary hyperparathyroidism each year from parathyroid adenoma[4].

Incidence

  • A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism.
  • Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease.

Age

  • They can occur at any age[5].

Gender

  • Women are affected 3-times as often as men
References

References

  1. ↑ Edafe O, Collins EE, Ubhi CS, Balasubramanian SP (February 2018). “Current predictive models do not accurately differentiate between single and multi gland disease in primary hyperparathyroidism: a retrospective cohort study of two endocrine surgery units”. Ann R Coll Surg Engl. 100 (2): 140–145. doi:10.1308/rcsann.2017.0112. PMC 5838681. PMID 29022783.
  2. ↑ Wolfe SA, Sharma S. PMID 29939647. Missing or empty |title= (help)
  3. ↑ Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, Haigh PI, Adams AL (March 2013). “Incidence and prevalence of primary hyperparathyroidism in a racially mixed population”. J. Clin. Endocrinol. Metab. 98 (3): 1122–9. doi:10.1210/jc.2012-4022. PMC 3590475. PMID 23418315.
  4. ↑ Pamathy G, Jayarajah U, Wangmo T, Banagala A (2018). “Lithium-induced Symptomatic Hypercalcemia and Hyperparathyroidism in a Patient with Bipolar Affective Disorder: A Case Report and Review of Literature”. Indian J Psychol Med. 40 (4): 378–380. doi:10.4103/IJPSYM.IJPSYM_305_17. PMC 6065126. PMID 30093752. Vancouver style error: initials (help)
  5. ↑ Sahli ZT, Karipineni F, Zeiger MA (August 2017). “A garden of parathyroid adenomas”. BMJ Case Rep. 2017. doi:10.1136/bcr-2017-221130. PMC 5747797. PMID 28775107.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Musadiq Ali M.B.B.S.[2]