Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Paroxysmal nocturnal hemoglobinuria physical examination
Introduction
Overview
Overview
Patients with paroxysmal nocturnal hemoglobinuria usually appear tired. Physical examination of patients with PNH is usually remarkable for fever, skin pallor, skin ecchymoses and skin nodules. Physical examination may show abdominal distension if PNH is associated with Budd-Chiari syndrome.
Physical Examination
Physical Examination
Appearance of the Patient
- Patients with paroxysmal nocturnal hemoglobinuria usually appear tired
Vital Signs
- Fever may be present due to infections
Skin
- Pallor
- Skin ecchymoses
- Skin nodules if it is associated with dermal vein thrombosis
HEENT
- Mucosal pallor
Neck
- Neck examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Lungs
- Pulmonary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Heart
- Cardiovascular examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Abdomen
- Abdominal distention if associated with Budd-Chiari syndrome[1]
- Hepatomegaly
- Splenomegaly
Genitourinary
- Genitourinary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
References
References
- ↑ Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP; et al. (2016). “Redefining Budd-Chiari syndrome: A systematic review”. World J Hepatol. 8 (16): 691–702. doi:10.4254/wjh.v8.i16.691. PMC 4909431. PMID 27326316.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [3]