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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Pertussis other diagnostic studies

Introduction

Overview

Overview

Pertussis can also be diagnosed using direct flourescent antibody (DFA) and pulsed-field gel eletrophoresis tests.

Other Diagnostic Studies

Other Diagnostic Studies

  • Direct fluorescent antibody (DFA)
    • DFA is inexpensive and may provide rapid results.[1]
    • It’s drawbacks, however, include poor sensitivity and specificity.[1]
  • Pulsed-field gel electrophoresis (PFGE)
    • PFGE is a DNA fingerprinting technique that has the following advantages:[2]
      • Highly discriminating in its results[3]
      • Easily applicable to Bordetella pertussis[3]
      • Stable and easily reproduced[3]
    • PFGE’s drawbacks include duration of time to perform as well as required a specifically trained and skilled technician.[3]
References

References

  1. ↑ 1.0 1.1 Miagkaia IP (1978). “[Antireticular cytotoxic serum as an agent for stimulating the immunity system]”. Zh. Mikrobiol. Epidemiol. Immunobiol. (in Russian) (12): 82–6. PMID 85400.
  2. ↑ Brown DD, Juhl RP, Warner SL (1979). “Effects of hypocholesterolemic interventions on digoxin bioavailability”. Drug Metab. Rev. 9 (1): 107–17. PMID 446263.
  3. ↑ 3.0 3.1 3.2 3.3 “Pulsed-field Gel Electrophoresis (PFGE) | Pathogens and Protocols | PulseNet | CDC”.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian M.D.; Aditya Govindavarjhulla, M.B.B.S. [2]; Luke Rusowicz-Orazem, B.S.; Yazan Daaboul, M.D.