In severe cases, immediate operation is necessary with application of a drainage system. All of these are done under general anesthesia. During the surgery, the cavity or place of phlegmonous process are washed with antiseptic, antibiotic solutions and proteolyic ferments.

In post-operative period, patients are treated with intravenous drips of detoxification, antibiotics, haemosorbtion, and vitaminotherapy. Additionally, the use of intravenous or intramuscular antistaphylococci γ-globulin or anatoxin can be taken as immunotherapy.

During operation of phlegmon dissection at any location, it is important:

1. To avoid spreading pus during the operation.
2. To take into account the cosmetic value of the operating site, especially phlegmmonous processes of the face.
3. To avoid damaging nerves, especially facial nerves. Use the correct incision line.