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Pirenzepine

Introduction

Overview

Overview

Pirenzepine (marketed by Merck Marker under the trade-name Gastrozepin) is used in the treatment of peptic ulcers, as it reduces gastric acid secretion and reduces muscle spasm. It is in a class of drugs known as Muscarinic receptor antagonists – acetylcholine being the neurotransmitter of the parasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight), the result being an increase in gastric motility and digestion. It has no effects on the brain and spinal cord as it cannot diffuse through the blood-brain barrier.

Pirenzepine has been investigated for use in myopia control.[1]

References

References

  1. ↑ Czepita D (2005). “Fundamentals of modern treatment of myopia”. Ann Acad Med Stetin. 51 (2): 5–9. PMID 16519089.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]