Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Pituitary apoplexy medical therapy
Introduction
Overview
Overview
The optimal therapy for pituitary apoplexy depends upon the presentationn of the patient. The emphasis is on early hemodynamic stabilization of the patient, with evaluation for signs of pituitary hormones deficiency. Life threatening hypopituitarism must be treated with replacement of hormones.
Medical Therapy
Medical Therapy
Medical treatment consists of:[1][2][3]
- Hemodynamic stabilization of the patient with evaluation for signs of pituitary hormones deficiency and electrolyte abnormalities.
- Most patients have life threatening hypopituitarism. Replace hormones with:
- High-dose corticosteroids
- Sex hormones (estrogen/testosterone)
- Thyroid hormone
- Evidence is also growing for the need to replace growth hormone.
References
References
- ↑ Veldhuis JD, Hammond JM (1980). “Endocrine function after spontaneous infarction of the human pituitary: report, review, and reappraisal”. Endocr. Rev. 1 (1): 100–7. doi:10.1210/edrv-1-1-100. PMID 6785084.
- ↑ Oelkers W (1996). “Adrenal insufficiency”. N. Engl. J. Med. 335 (16): 1206–12. doi:10.1056/NEJM199610173351607. PMID 8815944.
- ↑ De Ycaza AE, Chang AY, Jensen JR, Khan Z, Erickson D (2015). “Approach to the management of rare clinical presentations of macroprolactinomas in reproductive-aged women”. Case Rep Womens Health. 8: 9–12. doi:10.1016/j.crwh.2015.09.001. PMC 5033506. PMID 27668187.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]