Plantar warts, can often be differentiated from helomata, corns, by close observation of skin striations. Feet, like hands, are covered in skin striae, which are more commonly called fingerprints. With plantar warts, the skin striae go around the lesion; if the lesion is not a plantar wart, the cells’ DNA is not altered and the striations continue across the top layer of the skin. Plantar warts tend to be painful on application of pressure from eithe side of the lesion rather than direct pressure. Helomata tend to be painful on direct pressure rather than pressure from either side.

The difference between plantar warts and warts elsewhere on the body is that warts are generally outgrowth lesions, but on the bottom of the foot, they are pushed inward by the pressure of walking. Since the skin on the bottom of the foot tends to be thicker than elsewhere, the treatment of plantar warts is more difficult.

Your doctor may want to cut into a wart (called a biopsy) to confirm that it is not a corn, callus, skin cancer, or other similar-appearing growth.