Plesiomonas shigelloides

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Plesiomonas shigelloides is a Gram-negative, rod-shaped bacterium which has been isolated from freshwater, freshwater fish, and shellfish and from many types of animals including cattle, goats, swine, cats, dogs, monkeys, vultures, snakes, and toads.

Infections from this organism cause gastroenteritis followed by septicemia in immune deficient patients. It is placed among the Enterobacteriaceae.

• Plesiomonas shigelloides^[1]

• 1. Immunocompetent hosts or severe Infection

• Preferred regimen: Ciprofloxacin 500 mg PO bid or 400 mg IV q12h
• Alternative regimen (1): Ofloxacin 300 mg PO bid
• Alternative regimen (2): Norfloxacin 400 mg PO bid
• Alternative regimen (3): TMP-SMX DS PO bid for 3 days
• Alternative regimen (4): Ceftriaxone 1-2 g IV qd in severe cases

• 2. Immunocompromised hosts

• Preferred regimen: Ciprofloxacin 500 mg PO bid for 3 days
• Alternative regimen (1): Ofloxacin 300 mg PO bid
• Alternative regimen (2): Norfloxacin 400 mg PO bid
• Alternative regimen (3): TMP-SMX DS PO bid for 3 days if susceptible

• 
  Gram-stained photomicrograph reveals the presence of numerous Gram-negative Plesiomonas shigelloides bacteria. From Public Health Image Library (PHIL). ^[2]

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