Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Plexiform neurofibroma
Introduction
A plexiform neurofibroma is a tumor of the peripheral nerves which is common in individuals with neurofibromatosis type I, and indeed is diagnostic of that condition. The tumor occurs when Schwann cells multiply out of control within the nerve sheath. While typically benign, the tumor occasionally may become malignant. The tumors are often painful or disfiguring and may lead to disability.
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