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Poly(adp-ribose) polymerase family member 14

Introduction

Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene. [1]

Function

Function

Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).

References

References

  1. ↑ “Entrez Gene: Poly(ADP-ribose) polymerase family member 14”. Retrieved 2016-03-02.
Further reading

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.