Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Polyarthritis with joint swelling, fever, and weight loss
Introduction
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Physical examination | ||||||||||||||||||
| Lab Findings | Imaging | Histopathology | |||||||||||||||||
| Joint Swelling | Fever | Weight loss | Claudication | Morning stiffness | Local erythema | Skin manifestation | CBC | ESR | Synovial fluid | Other | X-ray | CT scan | Other | ||||||
| Polyarthritis | Infectious arthritis | Lyme disease[1] | + | + | +/- | +/- | – | – | Erythema migrans | Leukopenia, Thrombocytopenia | – | Cell counts 500-98,000/µL | Microscopic hematuria, Proteinuria, ↑ALT or AST | – | – | – | Fibrosis of the deeper dermis and hyalinization of collagen bundles | Serologic tests | Erythema migrans |
| Bacterial endocarditis[2] | + | + | + | – | – | +/- | Janeway lesions, Osler nodes, Roth spots | Normochromic-normocytic anemia | ↑ | ↑WBC, S. aureus in culture | Hyperglobulinemia, Cryoglobulinemia | Joint erosion and effusion | – | – | Vegetation or intracardiac abscess demonstrating active endocarditis | Echocardiography (TTE) | Vertebral osteomyelitis | ||
| Polyarticular pain | Viral arthritis | Parvovirus[3] | + | + | +/- | – | – | – | Fifth disease/ Erythema infectiosum | Aplastic crisis | ↑ | Normal | ANA, RF, CRP | Joint swelling | – | – | Immune complex deposition | Parvovirus IgM antibody | Transient aplastic crisis, Fetal infection |
References
- ↑ Lantos PM (2015). “Chronic Lyme disease”. Infect Dis Clin North Am. 29 (2): 325–40. doi:10.1016/j.idc.2015.02.006. PMC 4477530. PMID 25999227.
- ↑ Soor P, Sharma N, Rao C (2017). “Multifocal Septic Arthritis Secondary to Infective Endocarditis: A Rare Case Report”. J Orthop Case Rep. 7 (1): 65–68. doi:10.13107/jocr.2250-0685.692. PMC 5458702. PMID 28630844.
- ↑ Moore TL (July 2000). “Parvovirus-associated arthritis”. Curr Opin Rheumatol. 12 (4): 289–94. PMID 10910181.
Editor-In-Chief:
C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]