Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Polycystic kidney disease laboratory findings
Introduction
Overview
Overview
Common laboratory findings in polycystic kidney disease are urinary abnormalities including reduction in concentration capacity, hypocitraturia, hematuria, and proteinuria. Hyperuricemia is also a common finding and is a risk factor for disease progression and ESRD.
Laboratory Findings
Laboratory Findings
Laboratory findings in polycystic kidney disease are usually confined to urinary abnormalities, which include:[1]
- Reduction in maximal urine concentration after water deprivation and ADH administration (usually first manifestation of disease)
- Hypocitraturia in 65% on patients
- Hyperuricemia in 20% of patients
- Hyperoxaluria in 20% of patients
- Low urine pH
- Hematuria (microscopic or macroscopic)
- Proteinuria usually less than 1 g/day
References
References
- ↑ Fick GM, Gabow PA (1994). “Natural history of autosomal dominant polycystic kidney disease”. Annu Rev Med. 45: 23–9. doi:10.1146/annurev.med.45.1.23. PMID 8198379.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2], Serge Korjian,Yazan Daaboul