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Porphyria cutanea tarda overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Overview

Porphyria cutanea tarda (PCT) is the most common subtype of porphyria. The disorder results from low levels of the enzyme responsible for the fifth step in heme production. Heme is a vital molecule for all of the body’s organs. It is a component of hemoglobin, the molecule that carries oxygen in the blood.

Historical Perspective

Historical Perspective

Classification

Classification

Pathophysiology

Pathophysiology

Causes

Causes

Differentiating Porphyria cutanea tarda from Other Diseases

Differentiating Porphyria cutanea tarda from Other Diseases

Epidemiology and Demographics

Epidemiology and Demographics

Risk Factors

Risk Factors

Screening

Screening

Natural History, Complications, and Prognosis

Natural History, Complications, and Prognosis

Diagnosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Treatment

Medical Therapy

Surgery

Prevention

References

References

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