
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Portal vein thrombosis epidemiology and demographics
Introduction
Overview
Overview
The incidence of portal vein thrombosis in cirrhosis patients is unknown. The prevalence of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries. The overall mortality rate of portal vein thrombosis is less than 10% except for patients with malignancy or cirrhosis. Patients of all age groups may develop portal vein thrombosis. There is no racial predilection to portal vein thrombosis. Portal vein thrombosis affects men and women equally.
Epidemiology and Demographics
Epidemiology and Demographics
Incidence
Prevalence
- The prevalence of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries.[1][2]
- The prevalence of portal vein thrombosis is less than 1000 per 100,000 in patients with compensated cirrhosis, but is 8000-25000 per 100,000 in patients who are candidates for liver transplantation.[3][4][5]
Mortality rate
- The overall mortality rate of portal vein thrombosis is less than 10% except for patients with malignancy or cirrhosis.[1]
- The mortality rate of portal vein thrombosis in patients with malignancy or cirrhosis about 26%.[6]
- In patients with chronic portal vein thrombosis one-year survival alters from 80% to 95%, and 3-year survival varies from 75% to 90%.[7]
Age
- Patients of all age groups may develop portal vein thrombosis.[1]
- The incidence of portal vein thrombosis increases with age and it commonly affects individuals 66-70 years in men and 69-74 years in women.[2]
Race
- There is no racial predilection to portal vein thrombosis.
Gender
- Portal vein thrombosis affects men and women equally.[2]
References
References
- β 1.0 1.1 1.2 1.3 Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). “Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment”. World J. Gastroenterol. 16 (2): 143β55. PMCΒ 2806552. PMIDΒ 20066733.
- β 2.0 2.1 2.2 Ogren M, Bergqvist D, BjΓΆrck M, Acosta S, Eriksson H, Sternby NH (2006). “Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies”. World J. Gastroenterol. 12 (13): 2115β9. PMCΒ 4087695. PMIDΒ 16610067.
- β Okuda K, Ohnishi K, Kimura K, Matsutani S, Sumida M, Goto N, Musha H, Takashi M, Suzuki N, Shinagawa T (1985). “Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients”. Gastroenterology. 89 (2): 279β86. PMIDΒ 4007419.
- β Francoz C, Belghiti J, Vilgrain V, Sommacale D, Paradis V, Condat B, Denninger MH, Sauvanet A, Valla D, Durand F (2005). “Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation”. Gut. 54 (5): 691β7. doi:10.1136/gut.2004.042796. PMCΒ 1774501. PMIDΒ 15831918.
- β Fimognari FL, Violi F (2008). “Portal vein thrombosis in liver cirrhosis”. Intern Emerg Med. 3 (3): 213β8. doi:10.1007/s11739-008-0128-0. PMIDΒ 18274708.
- β Chawla YK, Bodh V (2015). “Portal vein thrombosis”. J Clin Exp Hepatol. 5 (1): 22β40. doi:10.1016/j.jceh.2014.12.008. PMCΒ 4415192. PMIDΒ 25941431.
- β Parikh, Sameer; Shah, Riddhi; Kapoor, Prashant (2010). “Portal Vein Thrombosis”. The American Journal of Medicine. 123 (2): 111β119. doi:10.1016/j.amjmed.2009.05.023. ISSNΒ 0002-9343.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
