The symptoms of post-streptococcal glomerulonephritis typically develop one to three weeks after exposure to group A streptococcal throat infection and 3 to 6 weeks after group A streptococcal skin infection. Common complications of post-streptococcal glomerulonephritis include severe nephritis, renal failure , atypical hemolytic uremic syndrome , refractory hypoxic respiratory failure, and seizures. Prognosis is generally excellent but depends upon age and co-morbidities.

• The symptoms of post-streptococcal glomerulonephritis typically develop one to three weeks after exposure to group A streptococcal throat infection and 3 to 6 weeks after group A streptococcal skin infection.
• If left untreated, patients with post-streptococcal glomerulonephritis may progress to develop renal failure.^[1]

Common complications of post-streptococcal glomerulonephritis include:^[2][3][4]

• Severe nephritis
• Renal failure
• Atypical hemolytic uremic syndrome
• Refractory hypoxic respiratory failure
• Seizures

• Prognosis is generally excellent.^[5][6]
• Some people develop recurrent proteinuria and renal dysfunction 10 to 40 years after the presentation.^[7]
• Age and presence of comorbidities are the most important prognostic factors for PSGN.
• Children have an excellent prognosis with a <1% rate of azotemia, and a 3-10% rate of non-nephrotic range proteinuria, microhematuria, and hypertension.
• The prognosis of PSGN in children might vary depending on individual co-morbidities, such as diabetes, obesity, and low birth weight.^[5]
• Elderly patients with PSGN who often have co-morbidities have a comparatively much poorer prognosis with a 60% rate of azotemia, 40% rate of congestive heart failure, and 20% rate of nephrotic syndrome.^[8][9]