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Post-thrombotic syndrome future or investigational therapies

Introduction

Overview

Overview

Future or Investigational Therapies

Future or Investigational Therapies

The field of PTS still holds many unanswered questions that are important targets for more research. Those include

  • fully defining the pathophysiology of PTS, including the role of inflammation and residual thrombus after completion of an appropriate duration of anticoagulant therapy
  • developing a PTS risk prediction model
  • role of thrombolysis (“clot-busting” drugs) in PTS prevention
  • defining the true efficacy of elastic compression stockings for PTS prevention (and if effective, elucidating the minimum compression strength necessary and the optimal timing and duration of compression therapy)
  • whether PTS prevention methods are necessary for patients with asymptomatic or distal DVT
  • additional treatment options for PTS with demonstrated safety and efficacy (compression and pharmacologic therapies)
References

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]