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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Pre-eclampsia natural history, complications and prognosis

Introduction

Overview

Overview

Preeclampsic patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. Early clinical feature after 20 weeks of gestation include blood pressure ≥ 140/90 mmHg, proteinuria, evidence of maternal organ involvement. Common complications of preeclampsia include: intrauterin growth retardation (IUGR), uteroplacental insufficiency, fetal asphyxia or fetal death, maternal seizures, and maternal death. Long term complication of preeclampsia include: chronic hypertension, diabetes mellitus, ischemic heart disease, cerebrovascular disease, kidney disease, thromboembolism, hypothyroidism, and impaired memory. Prognosis is generally good after delivery and controlling maternal hypertension. The five-year mortality rate of the patients with preeclampsia is approximately 0.4%.

Natural History, Complications and Prognosis

Natural History, Complications and Prognosis

  • Preeclampsic patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. [1]
  • Early clinical feature after 20 weeks of gestation include blood pressure ≥ 140/90 mmHg, proteinuria, evidence of maternal organ involvement.
References

References

  1. ↑ Brown, Mark A.; Magee, Laura A.; Kenny, Louise C.; Karumanchi, S. Ananth; McCarthy, Fergus P.; Saito, Shigeru; Hall, David R.; Warren, Charlotte E.; Adoyi, Gloria; Ishaku, Salisu (2018). “Hypertensive Disorders of Pregnancy”. Hypertension. 72 (1): 24–43. doi:10.1161/HYPERTENSIONAHA.117.10803. ISSN 0194-911X.
  2. ↑ Williams, David (2011). “Long-Term Complications of Preeclampsia”. Seminars in Nephrology. 31 (1): 111–122. doi:10.1016/j.semnephrol.2010.10.010. ISSN 0270-9295.
  3. ↑ Sibai, Baha M (2002). “The Magpie Trial”. The Lancet. 360 (9342): 1329. doi:10.1016/S0140-6736(02)11321-3. ISSN 0140-6736.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Ogheneochuko Ajari, MB.BS, MS [3]