Primary biliary cirrhosis other imaging findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis. Findings on an cholangiography diagnostic of primary biliary cirrhosis include shortened and diminished branches of the intrahepatic bile ducts. Transient elastography (Fibroscan) is used to evaluate the extent of fibrosis in advanced disease.

Other Imaging Findings

Cholangiography

Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis.
Findings on an cholangiography diagnostic of primary biliary cirrhosis include:^[1]^[2]
- Shortening of intrahepatic bile ducts
- Diminishing of intrahepatic bile ducts

Transient elastography (Fibroscan)

Findings on transient elastography may show reasonable correlation with the severity of cirrhosis:^[3]^[4]^[5]
- Increasing scarring of the liver is associated with increasing “stiffness” of the tissue.

References

↑ Legge DA, Carlson HC, Dickson ER, Ludwig J (1971). “Cholangiographic findings in cholangiolitic hepatitis. Syndrome of primary biliary cirrhosis”. Am J Roentgenol Radium Ther Nucl Med. 113 (1): 16–20. PMID 5096817.
↑ Lindor, Keith D.; Gershwin, M. Eric; Poupon, Raoul; Kaplan, Marshall; Bergasa, Nora V.; Heathcote, E. Jenny (2009). “Primary biliary cirrhosis”. Hepatology. 50 (1): 291–308. doi:10.1002/hep.22906. ISSN 0270-9139.
↑ Corpechot, Christophe; El Naggar, Ahmed; Poujol-Robert, Armelle; Ziol, Marianne; Wendum, Dominique; Chazouillères, Olivier; de Lédinghen, Victor; Dhumeaux, Daniel; Marcellin, Patrick; Beaugrand, Michel; Poupon, Raoul (2006). “Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC”. Hepatology. 43 (5): 1118–1124. doi:10.1002/hep.21151. ISSN 0270-9139.
↑ Foucher J, Chanteloup E, Vergniol J; et al. (2006). “Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study”. Gut. 55 (3): 403–8. doi:10.1136/gut.2005.069153. PMID 16020491.
↑ Xie L, Chen X, Guo Q, Dong Y, Guang Y, Zhang X (2012). “Real-time elastography for diagnosis of liver fibrosis in chronic hepatitis B”. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. 31 (7): 1053–60. PMID 22733854.

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[pmid5096817-1] Legge DA, Carlson HC, Dickson ER, Ludwig J (1971). “Cholangiographic findings in cholangiolitic hepatitis. Syndrome of primary biliary cirrhosis”. Am J Roentgenol Radium Ther Nucl Med. 113 (1): 16–20. PMID 5096817.

[LindorGershwin2009-2] Lindor, Keith D.; Gershwin, M. Eric; Poupon, Raoul; Kaplan, Marshall; Bergasa, Nora V.; Heathcote, E. Jenny (2009). “Primary biliary cirrhosis”. Hepatology. 50 (1): 291–308. doi:10.1002/hep.22906. ISSN 0270-9139.

[CorpechotEl_Naggar2006-3] Corpechot, Christophe; El Naggar, Ahmed; Poujol-Robert, Armelle; Ziol, Marianne; Wendum, Dominique; Chazouillères, Olivier; de Lédinghen, Victor; Dhumeaux, Daniel; Marcellin, Patrick; Beaugrand, Michel; Poupon, Raoul (2006). “Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC”. Hepatology. 43 (5): 1118–1124. doi:10.1002/hep.21151. ISSN 0270-9139.

[4] Foucher J, Chanteloup E, Vergniol J; et al. (2006). “Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study”. Gut. 55 (3): 403–8. doi:10.1136/gut.2005.069153. PMID 16020491.

[pmid22733854-5] Xie L, Chen X, Guo Q, Dong Y, Guang Y, Zhang X (2012). “Real-time elastography for diagnosis of liver fibrosis in chronic hepatitis B”. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. 31 (7): 1053–60. PMID 22733854.

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Primary biliary cirrhosis other imaging findings

Overview

Other Imaging Findings

References

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