Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Primary biliary cirrhosis secondary prevention
Introduction
Overview
Overview
Effective measures for the secondary prevention of primary biliary cirrhosis include follow up with liver function tests, thyroid status, upper GI endoscopy, bone mineral density, fat-soluble vitamin levels, ultrasound and alpha-fetoprotein levels to screen for hepatocellular carcinoma among aged men and patients with underlying cirrhosis.
Secondary Prevention
Secondary Prevention
- Effective measures for the secondary prevention of primary biliary cirrhosis include:[1][2][3][4]
- Follow up with liver function tests every 3 to 6 months.
- Follow up with thyroid status annually.
- Follow up with upper GI endoscopy to assess for development of varices every 2-3 years.
- Follow up with bone mineral density every 2-4 years, depending upon the baseline density and severity of cholestasis.
- Follow up with fat-soluble vitamin levels (Vitamin A,D&K) annually in patients with bilirubin >2mg/dl.
- Follow up with ultrasound and alpha-fetoprotein levels to screen for hepatocellular carcinoma every 6 to 12 months among aged men and patients with underlying cirrhosis.
References
References
- ↑ Chazouillères O, Wendum D, Serfaty L, Rosmorduc O, Poupon R (2006). “Long term outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome”. J. Hepatol. 44 (2): 400–6. doi:10.1016/j.jhep.2005.10.017. PMID 16356577.
- ↑ Poupon, Raoul; Chazouilleres, Olivier; Corpechot, Christophe; Chrétien, Yves (2006). “Development of autoimmune hepatitis in patients with typical primary biliary cirrhosis”. Hepatology. 44 (1): 85–90. doi:10.1002/hep.21229. ISSN 0270-9139.
- ↑ Colombato LA, Alvarez F, Côté J, Huet PM (1994). “Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis?”. Gastroenterology. 107 (6): 1839–43. PMID 7958699.
- ↑ Weyman RL, Voigt M (2001). “Consecutive occurrence of primary biliary cirrhosis and autoimmune hepatitis: a case report and review of the literature”. Am. J. Gastroenterol. 96 (2): 585–7. doi:10.1111/j.1572-0241.2001.03562.x. PMID 11232713.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]