Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Primary central nervous system lymphoma classification
Introduction
Overview
Overview
Primary CNS lymphomas are extranodal, malignant non-Hodgkin lymphomas of the diffuse large B-cell type that are confined to the brain, eyes, leptomeninges, or spinal cord, in the absence of systemic lymphoma. Primary CNS lymphomas are estimated to account for up to 1% of all lymphomas, 4–6% of all extranodal lymphomas, and about 3% of all CNS tumours. After a continuous rise in the incidence of primary CNS lymphoma during the 1980s and 1990s, epidemiological data in high-income countries show a decrease in incidence, particularly among young patients with AIDS.
Classification
Classification
Primary central nervous system lymphoma may be classified according to the site of involvement of the central nervous system into 3 groups:[1]
- Parenchymal
- Non-Hodgkin B cell type / diffuse large B-cell non-Hodgkin’s lymphoma (most common)
- Non-Hodgkin T cell type
- Primary CNS involvement with Hodgkin disease
- Intravascular lymphoma
- Primary leptomeningeal lymphoma
- Primary dural lymphoma
References
References
- ↑ CNS lymphoma. Dr Henry Knipe and Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/cns-lymphoma-1. Accessed on February 17, 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]